← all 2021 Ford F150 Pickup 4WD trims
2021 Ford F150 Pickup 4WD — 3.5L 6-cyl, S10 automatic, 4WD
This 2021 Ford F150 Pickup 4WD (3.5L 6-cyl, S10 automatic, 4WD) takes regular (87-octane) gasoline. REGULAR
19
MPG combined (17 city / 23 hwy)
$3,300
est. fuel cost / year (EPA, 15k mi)
468 g/mi
tailpipe CO₂
Other 2021 Ford F150 Pickup 4WD trims
| Trim | Fuel | MPG | Fuel/yr |
|---|---|---|---|
| 2.7L 6-cyl, S10 automatic, 4WD | REGULAR | 21 | $2,950 |
| 3.5L 6-cyl, S10 automatic, 4WD | REGULAR | 20 | $3,100 |
| 2.7L 6-cyl, S10 automatic, 4WD | REGULAR | 20 | $3,100 |
| 3.0L 6-cyl, S10 automatic, 4WD | DIESEL | 23 | $3,400 |
EPA fuel type: Regular · class: Standard Pickup Trucks 4WD · retrieved 2026-06-14.