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2020 Mercedes-Benz E450 4matic (station wagon) — 3.0L 6-cyl, Automatic 9-spd, 4WD
This 2020 Mercedes-Benz E450 4matic (station wagon) (3.0L 6-cyl, Automatic 9-spd, 4WD) takes premium gasoline. PREMIUM
22
MPG combined (19 city / 26 hwy)
$3,500
est. fuel cost / year (EPA, 15k mi)
408 g/mi
tailpipe CO₂
The EPA lists this trim as premium because that's the fuel the manufacturer specified for its mileage test. Many such engines will run on regular with slightly lower power and MPG — but check your owner's manual to see whether premium is required or just recommended.
EPA fuel type: Premium · class: Midsize Station Wagons · retrieved 2026-06-14.