FuelFacts

← all 2010 Lexus RX 450h trims

2010 Lexus RX 450h — 3.5L 6-cyl, AV-S6 automatic, FWD

This 2010 Lexus RX 450h (3.5L 6-cyl, AV-S6 automatic, FWD) takes premium gasoline. PREMIUM

30
MPG combined (32 city / 28 hwy)
$2,340
est. fuel cost / year (today’s prices, 15k mi)
tailpipe CO₂

At today's AAA national average price ($4.68/gal, 2026-07-05) — the EPA's own price/date assumption isn't exposed in the public dataset, so we recompute this from the EPA's MPG figure and a sourced current price.

The EPA lists this trim as premium because that's the fuel the manufacturer specified for its mileage test. Many such engines will run on regular with slightly lower power and MPG — but check your owner's manual to see whether premium is required or just recommended.

EPA fuel type: Premium · class: Sport Utility Vehicle - 2WD · engine: 3.5L 6-cyl · transmission: AV-S6 automatic · drive: FWD · MPG retrieved 2026-07-24.