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2008 Mercedes-Benz E350 4matic (wagon) — 3.5L 6-cyl, Automatic 5-spd, AWD
This 2008 Mercedes-Benz E350 4matic (wagon) (3.5L 6-cyl, Automatic 5-spd, AWD) takes premium gasoline. PREMIUM
18
MPG combined (16 city / 21 hwy)
$3,900
est. fuel cost / year (today’s prices, 15k mi)
—
tailpipe CO₂
At today's AAA national average price ($4.68/gal, 2026-07-05) — the EPA's own price/date assumption isn't exposed in the public dataset, so we recompute this from the EPA's MPG figure and a sourced current price.
The EPA lists this trim as premium because that's the fuel the manufacturer specified for its mileage test. Many such engines will run on regular with slightly lower power and MPG — but check your owner's manual to see whether premium is required or just recommended.
EPA fuel type: Premium · class: Midsize Station Wagons · engine: 3.5L 6-cyl · transmission: Automatic 5-spd · drive: AWD · MPG retrieved 2026-07-24.