2022 Ford F150 Pickup 2WD FFV MPG & Specs — Real-World vs EPA, All Trims
Fuel grade varies by trim — see the breakdown below.
Is the 2022 Ford F150 Pickup 2WD FFV good on gas?
At up to 21 MPG combined, the 2022 Ford F150 Pickup 2WD FFV is better than average for a Standard Pickup Trucks 2WD — that class averages about 17.3 MPG across 1,486 EPA-tested versions, so it's a good pick on fuel for its size.
Real-world MPG vs the EPA number
The EPA figures above come from a standardized dynamometer test, not the open road — real-world MPG typically runs a bit lower depending on your driving, climate and terrain. That's true of every car on this site, old or new.
For its most efficient trim, the EPA estimates about $2,950 a year in fuel (15,000 miles) — roughly $246 a month.
2022 Ford F150 Pickup 2WD FFV trims & fuel economy
| Trim (engine / transmission) | Fuel | MPG | Fuel/yr (today's price) |
|---|---|---|---|
| 3.3L 6-cyl, S10 automatic, RWD | FLEX-FUEL | 21 | $2,950 |
| 5.0L 8-cyl, S10 automatic, RWD | FLEX-FUEL | 20 | $3,100 |
| 5.0L 8-cyl, S10 automatic, RWD | FLEX-FUEL | 19 | $3,300 |
2022 Ford F150 Pickup 2WD FFV specs
What the EPA test-car listings record for this model year — every combination sold is a row in the trims table above.
| Engine options | 3.3L 6-cyl · 5.0L 8-cyl |
| Transmission | S10 automatic |
| Drive type | RWD |
| EPA body class | Standard Pickup Trucks 2WD |
| Fuel | Flex-fuel |
| Tailpipe CO₂ | 423–461 g/mi |
Other years of the Ford F150 Pickup 2WD FFV
Similar cars (Standard Pickup Trucks 2WD)
Cars that take premium · Cheapest cars to fuel · Where fuel grade depends on the trim · Fuel guides
3 trim(s) · EPA FuelEconomy.gov data retrieved 2026-07-24 · fuel prices AAA national average as of 2026-07-05.