2001 Isuzu Hombre Pickup 2WD (FFV) MPG & Specs — Real-World vs EPA, All Trims
Fuel grade varies by trim — see the breakdown below.
Is the 2001 Isuzu Hombre Pickup 2WD (FFV) good on gas?
At up to 22 MPG combined, the 2001 Isuzu Hombre Pickup 2WD (FFV) is about average for a Small Pickup Trucks 2WD — that class averages about 20.5 MPG across 517 EPA-tested versions, so it's middle-of-the-road for its size.
Real-world MPG vs the EPA number
The EPA figures above come from a standardized dynamometer test, not the open road — real-world MPG typically runs a bit lower depending on your driving, climate and terrain. That's true of every car on this site, old or new.
This 2001 model was originally EPA-tested under the pre-2008 2-cycle method, which didn't account for highway speeds over 60 mph, air-conditioner use, or cold starts. When EPA overhauled the test for model year 2008, city ratings fell by about 12% and highway by about 8% on average industry-wide — and EPA retroactively adjusted every 1984-2007 rating to the stricter standard so old and new cars could be compared fairly. The MPG above is already on that modern scale — the window sticker on this car when it was new likely showed a higher, pre-2008-method number.
For its most efficient trim, the EPA estimates about $2,850 a year in fuel (15,000 miles) — roughly $238 a month.
2001 Isuzu Hombre Pickup 2WD (FFV) trims & fuel economy
| Trim (engine / transmission) | Fuel | MPG | Fuel/yr (today's price) |
|---|---|---|---|
| 2.2L 4-cyl, 5-spd manual, RWD | FLEX-FUEL | 22 | $2,850 |
| 2.2L 4-cyl, Automatic 4-spd, RWD | FLEX-FUEL | 19 | $3,300 |
2001 Isuzu Hombre Pickup 2WD (FFV) specs
What the EPA test-car listings record for this model year — every combination sold is a row in the trims table above.
| Engine options | 2.2L 4-cyl |
| Transmission | 5-spd manual · Automatic 4-spd |
| Drive type | RWD |
| EPA body class | Small Pickup Trucks 2WD |
| Fuel | Flex-fuel |
Other years of the Isuzu Hombre Pickup 2WD (FFV)
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2 trim(s) · EPA FuelEconomy.gov data retrieved 2026-07-24 · fuel prices AAA national average as of 2026-07-05.