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2025 Lexus RX 450h Plus AWD — 2.5L 4-cyl, AV-S6 automatic, AWD
This 2025 Lexus RX 450h Plus AWD (2.5L 4-cyl, AV-S6 automatic, AWD) takes premium gasoline. PREMIUM
35
MPG combined (36 city / 33 hwy)
$2,200
est. fuel cost / year (EPA, 15k mi)
89 g/mi
tailpipe CO₂
The EPA lists this trim as premium because that's the fuel the manufacturer specified for its mileage test. Many such engines will run on regular with slightly lower power and MPG — but check your owner's manual to see whether premium is required or just recommended.
EPA fuel type: Premium and Electricity · class: Small Sport Utility Vehicle 4WD · retrieved 2026-06-14.