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2010 Mercedes-Benz E350 Coupe — 3.5L 6-cyl, Automatic 7-spd, RWD
This 2010 Mercedes-Benz E350 Coupe (3.5L 6-cyl, Automatic 7-spd, RWD) takes premium gasoline. PREMIUM
20
MPG combined (17 city / 26 hwy)
$3,850
est. fuel cost / year (EPA, 15k mi)
—
tailpipe CO₂
The EPA lists this trim as premium because that's the fuel the manufacturer specified for its mileage test. Many such engines will run on regular with slightly lower power and MPG — but check your owner's manual to see whether premium is required or just recommended.
EPA fuel type: Premium · class: Subcompact Cars · retrieved 2026-06-14.